Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.58 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.58 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.58 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27460009 | 0.84 | GRIN2B (0.64) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27775556 | 0.82 | ALDH1A1 (0.45) | — | |
| SCHEMBL27579148 | 0.80 | GRIN2B (0.41) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27389763 | 0.80 | GRIN2B (0.58) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27458618 | 0.78 | GRIN2B (0.58) | GRIN2B | |
| SCHEMBL28785094 | 0.78 | ALDH1A1 (0.38) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27608551 | 0.77 | GRIN1 (0.45) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8548110 | 0.77 | GRIN2B (0.64) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27794004 | 0.76 | ALDH1A1 (0.39) | ACHE | |
| SCHEMBL27459289 | 0.75 | GRIN2B (0.54) | GRIN2BGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1235604-A | Benzoxazole derivatives having affinity for amino acid receptor binding sites | MERCK PATENT GMBH (DE) | 1999-11-17 | — | — | CN | claimed |
| CN-1235604-A | Benzoxazole derivatives having affinity for amino acid receptor binding sites | MERCK PATENT GMBH (DE) | 1999-11-17 | — | — | CN | disclosed |