Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6660824 | 0.79 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4CYP2D6HTR2C | |
| SCHEMBL28838197 | 0.75 | AKR1C1 (0.45) | SLC6A2SLC6A3SLC6A4CYP2D6HTR2C | |
| SCHEMBL27499030 | 0.75 | SLC22A1 (0.47) | SLC6A2SLC22A1SLC6A4 | |
| SCHEMBL8320731 | 0.71 | SLC22A1 (0.51) | SLC22A1SLC6A4 | |
| SCHEMBL4661013 | 0.71 | SLC6A2 (0.44) | SLC6A2SLC6A3SLC6A4CYP2D6HTR2C | |
| SCHEMBL18752266 | 0.71 | SLC6A2 (0.52) | SLC6A2SLC6A3SLC6A4CYP2D6HTR2C | |
| Hydrochloric Acid SCHEMBL8316995 | 0.71 | SLC22A1 (0.50) | SLC22A1SLC6A4 | |
| Hydrochloric Acid SCHEMBL4021178 | 0.70 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4CYP2D6HTR2C | |
| SCHEMBL28922772 | 0.69 | ADAM17 (0.42) | — | |
| SCHEMBL7629979 | 0.68 | SLC6A2 (0.38) | SLC6A2SLC6A3SLC6A4CYP2D6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441706-A2 | ANTIMUSCARINIC AEROSOL | Pharmacia & Upjohn Company (US) | 2004-08-04 | — | — | EP | claimed |
| WO-2003039464-A2 | ANTIMUSCARINIC AEROSOL | PHARMACIA & UPJOHN COMPANY (US) | 2003-05-15 | — | — | WO | claimed |