Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 2/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27499242 | 0.83 | ALB (0.43) | NPSR1ALDH1A1ESR1ESR2NPC1 | |
| SCHEMBL27499546 | 0.81 | ALDH1A1 (0.32) | ALDH1A1ESR1HTT | |
| SCHEMBL28149385 | 0.78 | NPSR1 (0.52) | NPSR1ALDH1A1ESR1ESR2NPC1 | |
| SCHEMBL6823836 | 0.75 | ESR1 (0.40) | NPSR1ALDH1A1ESR1ESR2NPC1 | |
| SCHEMBL27587730 | 0.75 | NPSR1 (0.40) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL75883 | 0.73 | NPSR1 (0.64) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL28148401 | 0.73 | NPSR1 (0.64) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL75885 | 0.73 | NPSR1 (0.64) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL9267992 | 0.73 | NPSR1 (0.48) | NPSR1ALDH1A1ESR1ESR2NPC1 | |
| SCHEMBL27427973 | 0.72 | ALDH1A1 (0.38) | ALDH1A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1539816-A | IL-8 receptor antagonists | ʷ��˿�������ȳ�ķ����˾ | 2004-10-27 | — | — | CN | disclosed |
| CN-1215990-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-05-05 | — | — | CN | disclosed |