SCHEMBL27587730

SCHEMBL27587730

NC(=O)N(c1ccccc1)c1ccc(Cl)c(Cl)c1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.40
ALDH1A1 P00352 4/20 0.39
KMT2A Q03164 4/20 0.39
NPC1 O15118 3/20 0.39
POLB P06746 2/20 0.39
HTT P42858 2/20 0.39
RAB9A P51151 2/20 0.39
CXCR2 P25025 2/20 0.35
CXCR1 P25024 1/20 0.35
ATM Q13315 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
DPP4 P27487 1/20 0.33
APAF1 O14727 1/20 0.33
TRPM8 Q7Z2W7 1/20 0.33
TSHR P16473 2/20 0.33
CACNA2D1 P54289 2/20 0.32
CACNA1B Q00975 2/20 0.32
CACNB1 Q02641 2/20 0.32
CACNA1C Q13936 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7508715 0.81 CXCR2 (0.44) NPSR1ALDH1A1KMT2ANPC1POLB
SCHEMBL6820187 0.81 PARP10 (0.38) NPSR1ALDH1A1KMT2ANPC1HTT
SCHEMBL7552627 0.81 TSHR (0.36) ALDH1A1KMT2ACXCR2CXCR1L3MBTL1
SCHEMBL27587734 0.81 CXCR2 (0.45) KMT2ACXCR2CXCR1ATMTSHR
SCHEMBL28757170 0.78 NPSR1 (0.47) NPSR1ALDH1A1KMT2ANPC1POLB
SCHEMBL6825106 0.77 PAX8 (0.43) NPSR1ALDH1A1KMT2ANPC1RAB9A
SCHEMBL6823974 0.76 NPC1 (0.42) ALDH1A1KMT2ANPC1HTTRAB9A
SCHEMBL28100008 0.75 CYP3A4 (0.50) NPSR1ALDH1A1KMT2ANPC1POLB
SCHEMBL27499552 0.75 NPSR1 (0.40) NPSR1ALDH1A1KMT2ANPC1POLB
SCHEMBL27935130 0.73 MAP2 (0.39) KMT2ANPC1RAB9AATMTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1539816-A IL-8 receptor antagonists ʷ��˿�������ȳ�ķ���޹�˾ 2004-10-27 CN disclosed