Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24424690 | 0.75 | NPC1 (0.34) | SMN1; SMN2RAB9ANPC1MLYCDTRPA1 | |
| SCHEMBL15944448 | 0.69 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LMNAHTTCRBN | |
| SCHEMBL8021260 | 0.69 | MLYCD (0.41) | ALDH1A1RAB9ANPC1MLYCDHPGD | |
| SCHEMBL15944449 | 0.68 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2LMNAHTTCRBN | |
| SCHEMBL17049 | 0.67 | KMT2A (0.40) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL28823227 | 0.66 | MLYCD (0.47) | ALDH1A1SMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL25468768 | 0.66 | NPC1 (0.43) | ALDH1A1SMN1; SMN2LMNACRBNRAB9A | |
| SCHEMBL31447792 | 0.65 | RAB9A (0.45) | ALDH1A1SMN1; SMN2HTTCRBNRAB9A | |
| SCHEMBL21263673 | 0.65 | — | — | |
| SCHEMBL2729285 | 0.65 | NPC1 (0.45) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |