Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27462923 | 0.83 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL813276 | 0.79 | CYP3A4 (0.36) | CYP2D6CYP3A4CYP2C9TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL27932999 | 0.79 | CYP3A4 (0.33) | CYP2D6CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL29213166 | 0.78 | BCHE (0.35) | CYP2D6CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL815618 | 0.78 | BCHE (0.35) | CYP2D6CYP3A4CYP2C9TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL30361351 | 0.77 | CYP3A4 (0.35) | CYP2D6CYP3A4CYP2C9TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL2272446 | 0.77 | CYP3A4 (0.35) | CYP2D6CYP3A4CYP2C9TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL7194666 | 0.77 | CYP3A4 (0.33) | CYP2D6CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL11590486 | 0.77 | BCHE (0.34) | CYP2D6CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL18242642 | 0.77 | CYP3A4 (0.36) | CYP2D6CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1229395-C | Process for producing vinyl compound polymer | SUMITOMO CHEMICAL CO (JP) | 2005-11-30 | — | — | CN | disclosed |
| CN-1386765-A | Process for producing vinyl compound polymer | SUMITOMO CHEMICAL CO (JP) | 2002-12-25 | — | — | CN | disclosed |