Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27487844 | 0.84 | MEN1 (0.35) | MEN1CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL6564038 | 0.75 | LCK (0.36) | TDP1 | |
| SCHEMBL27555319 | 0.73 | CDC25A (0.33) | HSD17B10TDP1ALDH1A1 | |
| SCHEMBL6563032 | 0.72 | ALDH1A1 (0.37) | MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL6562945 | 0.72 | PTPN1 (0.36) | MEN1KMT2APTGS2 | |
| SCHEMBL27502905 | 0.68 | DAO (0.34) | HSD17B10TDP1 | |
| SCHEMBL6564995 | 0.68 | LCK (0.35) | — | |
| SCHEMBL6562861 | 0.67 | PTPN1 (0.36) | KMT2APTGS2 | |
| SCHEMBL6562868 | 0.67 | PTPN1 (0.36) | KMT2APTGS2 | |
| SCHEMBL6562789 | 0.62 | PRMT6 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1214022-C | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2005-08-10 | — | — | CN | disclosed |
| CN-1423645-A | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2003-06-11 | — | — | CN | disclosed |