SCHEMBL6562789

SCHEMBL6562789

CCC1(c2ccc(C)s2)OCCO1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PRMT6 Q96LA8 1/20 0.33
HCAR3 P49019 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6564251 0.79 MEN1 (0.34)
SCHEMBL27589714 0.77
SCHEMBL6564495 0.76 ALDH1A1 (0.39)
SCHEMBL27489196 0.71
SCHEMBL6564321 0.70 LMNA (0.39)
SCHEMBL27487819 0.69
SCHEMBL25541307 0.68 HCAR3 (0.39) PRMT6HCAR3HCAR2
SCHEMBL14779113 0.64 TSHR (0.47)
SCHEMBL16024116 0.64 HCAR3 (0.36) PRMT6HCAR3HCAR2
SCHEMBL11543842 0.62 SLC6A2 (0.33) HCAR3HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1235824-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2004-05-19 EP disclosed
EP-1235824-A1 VITAMIN D ANALOGUES Galderma Research & Development, S.N.C. (FR) 2002-09-04 EP disclosed
WO-2001038320-A1 VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2001-05-31 WO disclosed