Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | METAP2 | P50579 | 2/20 | 0.54 |
| ▸ | METAP1 | P53582 | 2/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | COMT | P21964 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8510518 | 1.00 | ACHE (0.54) | ACHETSHRMETAP2METAP1MMP2 | |
| SCHEMBL8507966 | 1.00 | ACHE (0.54) | ACHETSHRMETAP2METAP1MMP2 | |
| SCHEMBL276921 | 0.98 | ACHE (0.56) | ACHETSHRMETAP2METAP1MMP2 | |
| SCHEMBL28871758 | 0.95 | ACHE (0.54) | ACHETSHRMETAP2METAP1MMP2 | |
| SCHEMBL27575713 | 0.95 | ACHE (0.54) | ACHETSHRMETAP2METAP1MMP2 | |
| SCHEMBL4276275 | 0.95 | ACHE (0.54) | ACHETSHRMETAP2METAP1MMP2 | |
| Hydrochloric Acid SCHEMBL28763289 | 0.95 | ACHE (0.54) | ACHETSHRMETAP2METAP1MMP2 | |
| SCHEMBL276385 | 0.82 | METAP2 (0.54) | ACHETSHRMETAP2METAP1MMP2 | |
| SCHEMBL29577533 | 0.82 | METAP2 (0.54) | ACHETSHRMETAP2METAP1MMP2 | |
| Oxyquinoline SCHEMBL5514040 | 0.81 | TSHR (0.75) | ACHETSHRMETAP2METAP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1245581-A | Organic light emitting device containing protection layer | UNIV PRINCETON (US) | 2000-02-23 | — | — | CN | disclosed |