Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.60 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7583988 | 1.00 | DRD2 (0.60) | DRD2KDM1AMAOBDRD3KMT2A | |
| SCHEMBL5519650 | 0.93 | DRD2 (0.55) | DRD2KDM1AMAOBDRD3KMT2A | |
| SCHEMBL5537816 | 0.93 | DRD2 (0.55) | DRD2KDM1AMAOBDRD3KMT2A | |
| SCHEMBL16524042 | 0.86 | KMT2A (0.52) | DRD2KDM1AMAOBDRD3KMT2A | |
| SCHEMBL30772788 | 0.84 | CYP2C9 (0.48) | DRD2KDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL19898547 | 0.84 | CYP2C9 (0.48) | DRD2KDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL4814305 | 0.81 | KDM1A (0.52) | DRD2KDM1AMAOBDRD3KMT2A | |
| SCHEMBL4627783 | 0.81 | KDM1A (0.52) | DRD2KDM1AMAOBDRD3KMT2A | |
| SCHEMBL13652282 | 0.81 | KCNA3 (0.60) | DRD2KDM1ADRD3KMT2AL3MBTL1 | |
| SCHEMBL30993286 | 0.80 | KMT2A (0.47) | DRD2KDM1AMAOBKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1242993-C | Heterocycle derivatives and drugs | NIPPON SHINYAKU CO LTD (JP) | 2006-02-22 | — | — | CN | disclosed |
| CN-1422255-A | Heterocycle derivatives and drugs | NIPPON SHINYAKU CO LTD (JP) | 2003-06-04 | — | — | CN | disclosed |