Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991143 | 0.91 | L3MBTL1 (0.48) | L3MBTL1LPAR1ROCK2ROCK1CYP3A4 | |
| SCHEMBL6989277 | 0.88 | MEN1 (0.45) | L3MBTL1LPAR1ROCK2ROCK1MEN1 | |
| SCHEMBL6994555 | 0.83 | CENPE (0.39) | L3MBTL1CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL7089304 | 0.79 | RAF1 (0.47) | L3MBTL1LPAR1MEN1KMT2ANPC1 | |
| SCHEMBL6990538 | 0.78 | TACR1 (0.59) | — | |
| SCHEMBL27463643 | 0.78 | LOXL2 (0.43) | — | |
| SCHEMBL6991045 | 0.77 | TP53 (0.48) | LPAR1TDP1ALDH1A1 | |
| SCHEMBL6991831 | 0.75 | TACR1 (0.39) | L3MBTL1TDP1MEN1KMT2ATRPM8 | |
| SCHEMBL6988032 | 0.75 | TACR1 (0.39) | L3MBTL1TDP1MEN1KMT2ATRPM8 | |
| SCHEMBL6988027 | 0.75 | TACR1 (0.39) | L3MBTL1TDP1MEN1KMT2ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1140172-A | Cyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-01-15 | — | — | CN | disclosed |