Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27665438 | 0.82 | SMN1; SMN2 (0.39) | KMT2AMEN1TSHRBRD4L3MBTL1 | |
| SCHEMBL5321972 | 0.82 | CTSA (0.41) | KMT2AMEN1CTSANPSR1LMNA | |
| SCHEMBL5323449 | 0.77 | CYP26A1 (0.43) | KMT2AMEN1CTSAATML3MBTL1 | |
| SCHEMBL1520420 | 0.74 | KMT2A (0.45) | KMT2AMEN1TSHRBRD4CTSA | |
| SCHEMBL9631351 | 0.71 | TDP1 (0.44) | KMT2AMEN1HTTDPP8DPP9 | |
| SCHEMBL3382822 | 0.71 | MEN1 (0.44) | KMT2AMEN1TSHRBRD4CTSA | |
| SCHEMBL5322444 | 0.71 | GABBR2 (0.49) | KMT2AMEN1FFAR1SMN1; SMN2LMNA | |
| SCHEMBL28396451 | 0.71 | KMT2A (0.49) | KMT2AMEN1TSHRL3MBTL1FFAR1 | |
| SCHEMBL28396453 | 0.71 | KMT2A (0.49) | KMT2AMEN1TSHRL3MBTL1FFAR1 | |
| SCHEMBL27665829 | 0.71 | SLC1A3 (0.41) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1196671-C | Mono-and disubstituted 3-propyl-gamma-aminobutyric acids | WARNER LAMBERT CO (US) | 2005-04-13 | — | — | CN | disclosed |