Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.40 |
| ▸ | GABRE | P78334 | 2/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28396453 | 1.00 | KMT2A (0.49) | KMT2AMEN1TSHRGABRPGABRD | |
| Hydrochloric Acid SCHEMBL18077188 | 0.98 | KMT2A (0.47) | KMT2AMEN1TSHRGABRPGABRD | |
| SCHEMBL7813526 | 0.82 | KMT2A (0.50) | KMT2AMEN1TSHRFFAR1L3MBTL1 | |
| SCHEMBL7900708 | 0.81 | KMT2A (0.49) | KMT2AMEN1TSHRFFAR1L3MBTL1 | |
| SCHEMBL7900705 | 0.81 | KMT2A (0.49) | KMT2AMEN1TSHRFFAR1L3MBTL1 | |
| SCHEMBL5457124 | 0.75 | TSHR (0.51) | KMT2AMEN1TSHRFFAR1L3MBTL1 | |
| SCHEMBL4931341 | 0.74 | SLC6A9 (0.45) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11659436 | 0.73 | TAAR1 (0.44) | KMT2AMEN1KDM4EPOLBHSD17B10 | |
| SCHEMBL19231144 | 0.73 | ALDH1A1 (0.41) | KMT2AKDM4EPOLBHSD17B10GAA | |
| SCHEMBL8284306 | 0.73 | ALDH1A1 (0.41) | KMT2AKDM4EPOLBHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635993-B | Substituted tricyclic heterocyclic compounds | 百时美施贵宝公司 | 2020-05-22 | — | — | CN | disclosed |