Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632676 | 0.86 | PDE5A (0.35) | TDP1KDM4EMAPK1ALDH1A1TAAR1 | |
| SCHEMBL9631927 | 0.80 | ADRA2A (0.49) | TDP1KDM4EMAPK1ALDH1A1KMT2A | |
| SCHEMBL9203944 | 0.79 | KDM4E (0.43) | TDP1KDM4EMAPK1ALDH1A1LMNA | |
| SCHEMBL7783897 | 0.79 | ADRA1A (0.42) | TDP1KDM4EMAPK1ALDH1A1KMT2A | |
| SCHEMBL5057097 | 0.79 | ADRA1A (0.42) | TDP1KDM4EMAPK1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL8781949 | 0.78 | BLM (0.44) | TDP1KDM4EMAPK1ALDH1A1KMT2A | |
| SCHEMBL19231144 | 0.77 | ALDH1A1 (0.41) | TDP1KDM4EALDH1A1TAAR1KMT2A | |
| SCHEMBL9094407 | 0.77 | HTT (0.40) | TDP1MAPK1ALDH1A1TAAR1KMT2A | |
| SCHEMBL8133440 | 0.77 | HTT (0.40) | TDP1MAPK1ALDH1A1TAAR1KMT2A | |
| SCHEMBL8284306 | 0.77 | ALDH1A1 (0.41) | TDP1KDM4EALDH1A1TAAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145998-A | Reduction of oxime or silyloxime | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0237305-B1 | A METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-03 | — | — | EP | disclosed |
| EP-0237305-A2 | A method for producing optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-09-16 | — | — | EP | disclosed |