Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.35 |
| ▸ | NPC1 | O15118 | 10/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.34 |
| ▸ | POLB | P06746 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11983825 | 0.57 | NPC1 (0.46) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL15827302 | 0.55 | NPC1 (0.45) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL12230559 | 0.55 | ALDH1A1 (0.62) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL3628239 | 0.55 | MAOA (0.60) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL29503343 | 0.55 | MAOA (0.60) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL29638852 | 0.55 | MAOA (0.60) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL24610008 | 0.53 | TSHR (0.39) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL23568057 | 0.53 | KDM4E (0.36) | SMN1; SMN2TP53MAPTKDM4EALDH1A1 | |
| SCHEMBL20267194 | 0.53 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL8546257 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1204323-A | Use of tricyclic 1,4-dihydro-1,4-dioxo-1 H-naphthalene derivatives, resulting novel compounds and therapeutical use thereof | INNOTHERA LAB SA (FR) | 1999-01-06 | — | — | CN | disclosed |