Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19471892 | 0.83 | HDAC1 (0.49) | ALDH1A1ALOX5MEN1KMT2AHDAC1 | |
| SCHEMBL14275595 | 0.83 | HDAC1 (0.49) | ALDH1A1ALOX5MEN1KMT2AHDAC1 | |
| SCHEMBL17784780 | 0.83 | HDAC1 (0.49) | ALDH1A1ALOX5MEN1KMT2AHDAC1 | |
| SCHEMBL14275593 | 0.81 | HSD11B1 (0.52) | L3MBTL1ALDH1A1MGLLALOX5HSD11B1 | |
| SCHEMBL31334837 | 0.81 | ATM (0.52) | ATML3MBTL1ALDH1A1MGLLALOX5 | |
| SCHEMBL14275600 | 0.81 | HTR2C (0.45) | ALDH1A1MGLLALOX5ROCK2 | |
| SCHEMBL18048600 | 0.80 | ROCK2 (0.47) | ALDH1A1MGLLROCK2FPR1FPR2 | |
| SCHEMBL7927546 | 0.80 | MEN1 (0.50) | ALDH1A1ROCK2MEN1KMT2AFPR1 | |
| SCHEMBL5193387 | 0.80 | MEN1 (0.50) | ALDH1A1ROCK2MEN1KMT2AFPR1 | |
| SCHEMBL7933807 | 0.80 | MEN1 (0.50) | ALDH1A1ROCK2MEN1KMT2AFPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1341594-A | Substituted pyrrolidone, thiazolidone or oxazolidone as herbicide | ZENECA LTD (GB) | 2002-03-27 | — | — | CN | disclosed |
| CN-1153512-A | Substituted pyrrolidones, thiazolidinones or oxazolidinones as herbicides | ZENECA LTD (GB) | 1997-07-02 | — | — | CN | disclosed |