Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 2/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND2 | P30279 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28555588 | 0.87 | KDR (0.57) | KDM4APOLBNPC1RAB9AKDM4B | |
| SCHEMBL10772697 | 0.86 | HDAC3 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA4ADRA1D | |
| SCHEMBL16702338 | 0.84 | ATR (0.52) | KDM4CMAPT | |
| SCHEMBL28555585 | 0.82 | CETP (0.51) | KDM4ELMNAPOLBMAPTALDH1A1 | |
| SCHEMBL29112640 | 0.81 | NTRK1 (0.45) | KDM4EKDM4AKDM6BKDM5CKDM4C | |
| SCHEMBL17144825 | 0.77 | KDM4E (0.54) | ADRA1DADRA1AADRA1BKDM4EATM | |
| SCHEMBL6019227 | 0.77 | HPGD (0.60) | CYP1A2LMNANPC1RAB9AMAPT | |
| SCHEMBL27083586 | 0.77 | JAK1 (0.43) | KDM4EKDM4AKDM6BKDM5CKDM4C | |
| SCHEMBL6020308 | 0.76 | MAPK1 (0.66) | LMNAPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL6019359 | 0.76 | RAB9A (0.54) | KDM4EPOLBNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152015-C | Piperazine devivatives and process for preparation thereof | ������ҩ��ʽ���� | 2004-06-02 | — | — | CN | disclosed |
| CN-1196724-A | Novel piperazine derivative and process for producing the same | SAMJIN PHARM CO LTD (KR) | 1998-10-21 | — | — | CN | disclosed |