SCHEMBL6019359

SCHEMBL6019359

Cc1ccsc1C(=O)Nc1ccccc1-c1ccccn1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 11/20 0.54
NPC1 O15118 9/20 0.54
PPARG P37231 1/20 0.54
NCOR2 Q9Y618 1/20 0.54
HPGD P15428 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NAMPT P43490 1/20 0.50
GRM1 Q13255 1/20 0.48
PKM P14618 2/20 0.48
POLB P06746 2/20 0.46
NTRK1 P04629 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MAPT P10636 3/20 0.43
PDE10A Q9Y233 1/20 0.42
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1015339 0.79 ALB (0.57) RAB9ANPC1HPGDSMN1; SMN2NAMPT
SCHEMBL27474433 0.79 RAB9A (0.66) RAB9ANPC1PPARGNCOR2HPGD
SCHEMBL6018733 0.79 RAB9A (0.43) RAB9ANPC1HPGDNTRK1MEN1
SCHEMBL9259634 0.78 HPGD (0.63) RAB9ANPC1PPARGNCOR2HPGD
SCHEMBL28555588 0.77 KDR (0.57) RAB9ANPC1HPGDPOLB
SCHEMBL27508370 0.76 CHRNB2 (0.45) RAB9ANPC1POLBMAPTKDM4E
SCHEMBL12974613 0.76 RAB9A (0.50) RAB9ANPC1PPARGNCOR2HPGD
SCHEMBL17552234 0.76 KDR (0.60) RAB9ANPC1PPARGNCOR2HPGD
SCHEMBL29911317 0.76 KDR (0.60) RAB9ANPC1PPARGNCOR2HPGD
SCHEMBL14156256 0.76 HPGD (0.51) RAB9ANPC1PPARGNCOR2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060178513-A1 Pyridinylanilides BAYER CROPSCIENCE AG (DE) 2006-08-10 US disclosed
EP-1656020-A2 PYRIDINYLANILIDES Bayer CropScience AG (DE) 2006-05-17 EP disclosed
WO-2005004606-A2 PYRIDINYLANILIDES BAYER CROPSCIENCE AG (DE) 2005-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060178513-A1 Pyridinylanilides C3AR1, C5, PADI1 RAB9A 1263/4885NPC1 4734/4885PPARG 4293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.