Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831372 | 0.83 | NOTUM (0.62) | NOTUMTP53HSD17B10POLBLMNA | |
| SCHEMBL2203840 | 0.82 | NOTUM (0.83) | NOTUMTP53HSD17B10POLBLMNA | |
| SCHEMBL28631380 | 0.78 | HSD17B10 (0.70) | NOTUMHSD17B10POLBLMNAALDH1A1 | |
| SCHEMBL24011118 | 0.78 | LMNA (0.71) | NOTUMTP53HSD17B10POLBLMNA | |
| SCHEMBL8141514 | 0.76 | LMNA (0.60) | NOTUMTP53HSD17B10POLBLMNA | |
| SCHEMBL27691365 | 0.76 | NOTUM (0.72) | NOTUMTP53HSD17B10MAPK1 | |
| SCHEMBL6721657 | 0.75 | NOTUM (0.64) | NOTUMTP53LMNAALDH1A1TSHR | |
| SCHEMBL156256 | 0.75 | NOTUM (0.82) | NOTUMTP53POLBLMNAALDH1A1 | |
| SCHEMBL11853725 | 0.74 | ESR1 (0.69) | NOTUMTP53HSD17B10POLBLMNA | |
| SCHEMBL12245561 | 0.74 | ALOX15 (0.53) | TP53HSD17B10POLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1168667-A | Pyridopyrimidones, quinolines and fused N-heretocycles as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-12-24 | — | — | CN | disclosed |