Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 2/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.41 |
| ▸ | GABRP | O00591 | 3/20 | 0.41 |
| ▸ | GABRD | O14764 | 3/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.41 |
| ▸ | GABRE | P78334 | 3/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27775280 | 0.89 | CPN1 (0.42) | CPN1CPB2MAPTGABRA5GABRB2 | |
| Hydrochloric Acid SCHEMBL28034127 | 0.88 | CPN1 (0.41) | CPN1CPB2MAPTGABRA5GABRB2 | |
| SCHEMBL5967361 | 0.86 | GABRP (0.48) | MAPTGABRA5GABRB2GABRA1GABRA4 | |
| SCHEMBL6566358 | 0.82 | GABRP (0.45) | MAPTGABRA5GABRB2GABRA1GABRA4 | |
| SCHEMBL6050191 | 0.81 | CPN1 (0.47) | CPN1CPB2GABRA5GABRB2GABRA1 | |
| SCHEMBL12462120 | 0.81 | CPN1 (0.47) | CPN1CPB2GABRA5GABRB2GABRA1 | |
| SCHEMBL1226217 | 0.81 | ALDH1A1 (0.44) | MAPTGABRA5GABRB2GABRA1GABRA4 | |
| SCHEMBL28034069 | 0.79 | CPN1 (0.46) | CPN1CPB2MAPTGABRA5GABRB2 | |
| SCHEMBL149437 | 0.76 | CPN1 (0.37) | CPN1CPB2OPRD1 | |
| SCHEMBL149436 | 0.76 | CPN1 (0.37) | CPN1CPB2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102439007-A | Amide derivatives | DAIICHI SANKYO CO LTD | 2012-05-02 | — | — | CN | disclosed |
| CN-1131665-A | Piperazine derivatives, medicaments comprising these compounds, their use and processes for their preparation | THOMAE GMBH DR K (DE) | 1996-09-25 | — | — | CN | disclosed |