Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 2/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.35 |
| ▸ | GABRP | O00591 | 3/20 | 0.35 |
| ▸ | GABRD | O14764 | 3/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.35 |
| ▸ | GABRE | P78334 | 3/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25429420 | 0.82 | ALDH1A1 (0.49) | MAPTGABRA5GABRB2GABRA1GABRA4 | |
| SCHEMBL27508607 | 0.79 | CPN1 (0.44) | CPN1CPB2MAPTITGB3ITGA2B | |
| Acetic Acid SCHEMBL29252175 | 0.78 | GNAI3 (0.42) | CPN1CPB2MAPTGNAI3GNAO1 | |
| SCHEMBL13259736 | 0.77 | CPN1 (0.33) | CPN1CPB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10272804 | 0.77 | CPN1 (0.38) | CPN1CPB2OPRD1SLC6A2SLC6A4 | |
| SCHEMBL28071209 | 0.76 | CPN1 (0.42) | CPN1CPB2ITGB3ITGA2BGABRA5 | |
| SCHEMBL13825689 | 0.74 | GNAO1 (0.38) | CPN1CPB2GNAI3GNAO1GNAI1 | |
| SCHEMBL20935045 | 0.74 | CPN1 (0.32) | CPN1CPB2 | |
| SCHEMBL1775857 | 0.74 | CPN1 (0.67) | CPN1CPB2GABRA5GABRB2GABRA1 | |
| SCHEMBL21919470 | 0.74 | CPN1 (0.37) | CPN1CPB2OPRD1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104876955-B | Arginase inhibitor and its treatment use | 马尔斯公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-103068830-B | Arginase inhibitors and therapeutic uses thereof | 马尔斯公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-104876955-A | Inhibitors Of Arginase And Their Therapeutic Applications | MARS INC | 2015-09-02 | — | — | CN | disclosed |