Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27602806 | 0.85 | KMT2A (0.53) | MEN1KMT2AHDAC1HDAC6ALDH1A1 | |
| SCHEMBL5265818 | 0.84 | MEN1 (0.57) | MEN1KMT2AKIF11PARP10PARP15 | |
| SCHEMBL30063441 | 0.84 | MEN1 (0.57) | MEN1KMT2AKIF11PARP10PARP15 | |
| Hydrochloric Acid SCHEMBL28748216 | 0.83 | KMT2A (0.52) | MEN1KMT2AHDAC1HDAC6ALDH1A1 | |
| SCHEMBL4311410 | 0.81 | MEN1 (0.53) | MEN1KMT2AKIF11PARP10PARP15 | |
| SCHEMBL27565314 | 0.79 | KMT2A (0.52) | MEN1KMT2AHDAC1HDAC6ALDH1A1 | |
| SCHEMBL440172 | 0.79 | MEN1 (0.52) | MEN1KMT2AKIF11CA12CA1 | |
| SCHEMBL5260935 | 0.79 | MEN1 (0.52) | MEN1KMT2AKIF11 | |
| SCHEMBL17801666 | 0.79 | KMT2A (0.52) | MEN1KMT2AALDH1A1KIF11PARP10 | |
| SCHEMBL18147842 | 0.79 | ALDH1A1 (0.46) | MEN1KMT2AHDAC1HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800946-A | Urea compound, pharmaceutical composition and application thereof | 中国药科大学 | 2024-04-02 | — | — | CN | disclosed |
| CN-117355533-A | Novel compounds as protein kinase inhibitors | 株式会社LG化学 | 2024-01-05 | — | — | CN | disclosed |
| CN-116745279-A | Novel compounds as protein kinase inhibitors | 株式会社LG化学 | 2023-09-12 | — | — | CN | disclosed |
| CN-109265471-A | FXR receptor stimulating agent | 海南轩竹医药科技有限公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-108883099-A | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | 石全 | 2018-11-23 | — | — | CN | disclosed |
| CN-108495850-A | Oxopyridine amide derivatives, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-105101959-B | Cyclic sulfonamide-containing derivatives as hedgehog signaling pathway inhibitors | 南特知识产权控股有限责任公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-104981468-B | The piperazine heterocycle compound of benzimidazole 2, its pharmaceutical composition and its production and use | 上海汇伦生命科技有限公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-107074773-A | Substituted N, the formamide of 2 biaryl quinolin 4 and application thereof | 拜耳制药股份公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-107072985-A | Therapeutic inhibiting compound | 莱福斯希医药公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-101531631-B | Substituted pyridinones as modulators of p38 map kinase | PHARMACIA CORP | 2011-09-28 | — | — | CN | disclosed |
| CN-101903375-A | Carboxyl- or hydroxyl-substituted benzimidazole derivatives | HOFFMANN LA ROCHE | 2010-12-01 | — | — | CN | disclosed |
| CN-101531631-A | Substituted pyridinones as modulators of p38 map kinase | PHARMACIA CORP (US) | 2009-09-16 | — | — | CN | disclosed |
| CN-100486576-C | Substituted pyridones as modulators of P38MAP kinase | PHARMACIA CORP (US) | 2009-05-13 | — | — | CN | disclosed |
| CN-101035795-A | Thiazolyl dihydroindazoles | BOEHRINGER INGELHEIM INT (DE) | 2007-09-12 | — | — | CN | disclosed |
| CN-1283621-C | Alkyl urea vitamin A protagonist I | HOFFMANN LA ROCHE (CH) | 2006-11-08 | — | — | CN | disclosed |
| CN-1744899-A | Piperidine derivatives as CCR5 antagonists | SMITHKLINE BEECHAM CORP (US) | 2006-03-08 | — | — | CN | disclosed |
| CN-1646125-A | Substituted pyridones as modulators of P38MAP kinase | PHARMACIA CORP (US) | 2005-07-27 | — | — | CN | disclosed |
| CN-1555359-A | Alkyl urea vitamin A protagonist i | - | 2004-12-15 | — | — | CN | disclosed |
| CN-1237962-A | Pyrrolidinyl and pyrrolinyl ethylamine compounds as K agonists | PFIZER (US) | 1999-12-08 | — | — | CN | disclosed |