SCHEMBL27512331

SCHEMBL27512331

CC(C)c1ccc(C(C)C(=O)C(C)c2ccc(C(C)C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 4/20 0.48
CYP2D6 P10635 1/20 0.48
HIF1A Q16665 1/20 0.48
TYR P14679 2/20 0.48
KDM4E B2RXH2 1/20 0.47
MAPK1 P28482 1/20 0.47
USP5 P45974 1/20 0.45
PTGS2 P35354 5/20 0.45
KIF11 P52732 1/20 0.44
HTT P42858 1/20 0.43
LMNA P02545 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
ALDH1A1 P00352 1/20 0.42
PTGS1 P23219 4/20 0.42
AKR1C3 P42330 2/20 0.42
CXCR1 P25024 2/20 0.42
CXCR2 P25025 2/20 0.42
ALB P02768 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6551674 0.82 PTGS2 (0.65) CYP2C9CYP2D6HIF1AKDM4EMAPK1
SCHEMBL11749792 0.82 ESR1 (0.56) CYP2C9CYP2D6PTGS2LMNAMEN1
SCHEMBL4651605 0.82 PTGS2 (0.65) CYP2C9CYP2D6HIF1AKDM4EMAPK1
SCHEMBL4484070 0.80 CYP1A2 (0.52) CYP2D6PTGS2LMNASMN1; SMN2ALDH1A1
SCHEMBL23003791 0.80 GRM7 (0.47) KDM4EPTGS2HTTLMNAKMT2A
SCHEMBL2928062 0.79 PTGS2 (0.56) CYP2D6HIF1AKDM4EMAPK1PTGS2
SCHEMBL8833485 0.78 TSHR (0.55) TYRPTGS2KMT2ASMN1; SMN2ALDH1A1
SCHEMBL9577330 0.78 CYP2C9 (0.52) CYP2C9CYP2D6HIF1ATYRKDM4E
SCHEMBL12896284 0.77 HPGD (0.53) CYP2C9CYP2D6HIF1ATYRPTGS2
SCHEMBL11130803 0.77 HPGD (0.53) CYP2C9CYP2D6HIF1ATYRPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103958047-B Microcapsules and their use 弗门尼舍有限公司 2017-03-01 CN claimed
CN-103958047-A Microcapsules and their use FIRMENICH & CIE 2014-07-30 CN claimed
CN-107207994-A Photolabile acetal and ketal compounds for controlled release of active volatile carbonyl compounds 弗门尼舍有限公司 2017-09-26 CN disclosed
CN-103857707-B For the photo-labile latex of perfume releasing FIRMENICH S.A. (CH) 2016-04-13 CN disclosed
CN-103459573-B Balanced dynamic mixtures for controlled release of perfuming aldehydes and ketones FIRMENICH S.A. (CH) 2015-11-25 CN disclosed
CN-103958047-A Microcapsules and their use FIRMENICH & CIE 2014-07-30 CN disclosed
CN-103857707-A Photolabile latex for the release of perfumes FIRMENICH & CIE 2014-06-11 CN disclosed
CN-103459573-A Balanced dynamic mixtures for controlled release of perfuming aldehydes and ketones FIRMENICH & CIE 2013-12-18 CN disclosed
CN-102026988-B 3-substituted propanamines SK HOLDINGS CO LTD 2013-07-03 CN disclosed
CN-101679290-B 3- to 7-membered 1,3-diaza-4-oxo-heterocyclic derivatives capable of releasing active aldehydes or ketones FIRMENICH & CIE 2012-10-03 CN disclosed
CN-101605765-B Controlled release of reactive aldehydes and ketones from an equilibrated dynamic mixture FIRMENICH & CIE 2012-06-06 CN disclosed
CN-102026988-A 3-substituted propanamines SK HOLDINGS CO LTD 2011-04-20 CN disclosed
CN-101001832-B Use of dynamic mixtures for controlled fragrance release FIRMENICH & CIE 2010-05-05 CN disclosed
CN-101679290-A 3- to 7-membered 1,3-diaza-4-oxo-heterocyclic derivatives capable of releasing active aldehydes or ketones FIRMENICH & CIE 2010-03-24 CN disclosed
CN-101605765-A Controlled release of reactive aldehydes and ketones from an equilibrated dynamic mixture FIRMENICH & CIE (CH) 2009-12-16 CN disclosed
CN-100422300-C Fabric care compositions containing cationic polysiloxanes and methods of use thereof PROCTER & GAMBLE (US) 2008-10-01 CN disclosed
CN-101001832-A Use of dynamic mixtures for controlled fragrance release FIRMENICH & CIE (CH) 2007-07-18 CN disclosed
CN-1946703-A Substituted thiazole and pyrimidine derivatives as melanocortin receptor modulators TRANSTECH PHARMA INC (US) 2007-04-11 CN disclosed
CN-1252070-A 5,7-disubstituted 4-aminopyrido [2,3,-d] pyrimidine compounds and their use as adenosine kinase inhibitors ABBOTT LAB (US) 2000-05-03 CN disclosed