Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | BHMT | Q93088 | 3/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10800375 | 0.83 | LMNA (0.64) | LMNAKMT2AHSD17B10TDP1PLA2G4B | |
| SCHEMBL1104232 | 0.81 | LMNA (0.54) | LMNAKMT2AHSD17B10TDP1PLA2G4B | |
| SCHEMBL29006020 | 0.79 | LMNA (0.52) | LMNAKMT2AHSD17B10TDP1PLA2G4B | |
| SCHEMBL16715949 | 0.78 | LMNA (0.56) | LMNAKMT2AHSD17B10TDP1PLA2G4B | |
| SCHEMBL14865692 | 0.76 | PLA2G4B (0.55) | LMNAKMT2AHSD17B10TDP1PLA2G4B | |
| SCHEMBL19792798 | 0.76 | LMNA (0.59) | LMNAKMT2AHSD17B10TDP1PLA2G4B | |
| SCHEMBL9087634 | 0.75 | LMNA (0.52) | LMNAKMT2AHSD17B10TDP1PLA2G4B | |
| SCHEMBL12657077 | 0.75 | — | — | |
| SCHEMBL10796758 | 0.74 | LMNA (0.64) | LMNAKMT2AHSD17B10TDP1PLA2G4B | |
| SCHEMBL2048131 | 0.74 | TSHR (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1253442-C | Novel thiazine and pyrazine derivatives | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-04-26 | — | — | CN | disclosed |
| CN-1372553-A | Novel thiazine or pyrazine derivatives | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-10-02 | — | — | CN | disclosed |