SCHEMBL1104232

SCHEMBL1104232

O=C(O)CCSCC(O)CO

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.54
KMT2A Q03164 1/20 0.54
HSD17B10 Q99714 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
TSHR P16473 2/20 0.44
PLA2G4B P0C869 1/20 0.42
BHMT Q93088 3/20 0.41
CYP2C19 P33261 1/20 0.38
CYP1A2 P05177 2/20 0.34
TET2 Q6N021 3/20 0.33
KDM4A O75164 2/20 0.33
KDM4C Q9H3R0 2/20 0.33
KDM2A Q9Y2K7 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
TET3 O43151 1/20 0.33
ARG1 P05089 1/20 0.33
ARG2 P78540 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
SUCNR1 Q9BXA5 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9233298 0.88 TSHR (0.50) LMNAKMT2AHSD17B10TDP1TSHR
E388 SCHEMBL28018651 0.86 LMNA (0.67) LMNAKMT2AHSD17B10TDP1TSHR
E388 SCHEMBL28061251 0.86 LMNA (0.67) LMNAKMT2AHSD17B10TDP1TSHR
SCHEMBL1104269 0.86 BHMT (0.47) LMNAKMT2AHSD17B10TDP1TSHR
SCHEMBL10800375 0.84 LMNA (0.64) LMNAKMT2AHSD17B10TDP1TSHR
SCHEMBL1104282 0.84 BHMT (0.49) LMNATDP1TSHRPLA2G4BBHMT
SCHEMBL29006020 0.81 LMNA (0.52) LMNAKMT2AHSD17B10TDP1TSHR
SCHEMBL27513618 0.81 LMNA (0.52) LMNAKMT2AHSD17B10TDP1TSHR
SCHEMBL925175 0.78 LMNA (0.47) LMNATDP1ALDH1A1
SCHEMBL13380613 0.78 PLA2G4B (0.34) LMNAKMT2APLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388717-A1 POLYUREA ACRYLATE OLIGOMER CONTAINING PROTECTED GROUPS AND PREPARATION METHOD AND APPLICATION THEREOF UNIV ZHEJIANG (CN) 2025-12-25 US disclosed
CN-118667121-B Polyurea acrylate oligomer containing protected group, and preparation method and application thereof 浙江大学 2025-03-21 CN disclosed
CN-118667121-A Polyurea acrylate oligomer containing protected group, and preparation method and application thereof 浙江大学 2024-09-20 CN disclosed
EP-2692805-A1 INK COMPOSITION AND IMAGE FORMING METHOD FUJIFILM Corporation (JP) 2014-02-05 EP disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20100183540-A1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER JOTUN A/S (NO) 2010-07-22 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-5506267-A IMMUNOADJUVANT FOR BONE MARROW CELL GROWTH AFTERTREATMENT OF CHEMOTHERAPY OR RADIOTHERAPY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-04-09 US disclosed
EP-0641776-A2 Thioglycerol derivatives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-03-08 EP disclosed
EP-0638588-A1 Derivatives of 6,7-Dihydroxy-4-thiaheptonic acid and their use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-02-15 EP disclosed
EP-0638588-A1 Derivatives of 6,7-Dihydroxy-4-thiaheptonic acid and their use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-02-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388717-A1 POLYUREA ACRYLATE OLIGOMER CONTAINING PROTECTED GROUPS AND PREPARATION METHOD AND APPLICATION THEREOF DCTD, UMPS, IMPDH1 LMNA 1026/4885KMT2A 4033/4885HSD17B10 4041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.