Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 6/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594898 | 0.85 | PARP1 (0.39) | PARP10 | |
| SCHEMBL27528049 | 0.82 | SMN1; SMN2 (0.37) | ESR1 | |
| SCHEMBL27528054 | 0.80 | CA3 (0.33) | ESR1 | |
| SCHEMBL27605669 | 0.80 | CA12 (0.47) | — | |
| SCHEMBL27535699 | 0.78 | PLAU (0.47) | — | |
| SCHEMBL27516293 | 0.78 | KDM4E (0.38) | ESR1 | |
| SCHEMBL27515970 | 0.78 | PTK2 (0.36) | ACHEESR1 | |
| SCHEMBL27576101 | 0.78 | EGFR (0.41) | — | |
| SCHEMBL27499553 | 0.76 | ACMSD (0.43) | — | |
| SCHEMBL6823428 | 0.75 | KMT2A (0.38) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1539816-A | IL-8 receptor antagonists | ʷ��˿�������ȳ�ķ����˾ | 2004-10-27 | — | — | CN | disclosed |
| CN-1215990-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-05-05 | — | — | CN | disclosed |