Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 3/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127456 | 0.81 | ATR (0.55) | KDM4EALDH1A1HPGDHSD17B10PDE4D | |
| SCHEMBL27578290 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10PLD1 | |
| SCHEMBL29442179 | 0.81 | ATR (0.55) | KDM4EALDH1A1HPGDHSD17B10PDE4D | |
| SCHEMBL28539899 | 0.81 | ATR (0.55) | KDM4EALDH1A1HPGDHSD17B10PDE4D | |
| SCHEMBL28539901 | 0.81 | ATR (0.55) | KDM4EALDH1A1HPGDHSD17B10PDE4D | |
| SCHEMBL1928736 | 0.76 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10PLD1GRIN2D | |
| SCHEMBL31051684 | 0.75 | LMNA (0.47) | KDM4EALDH1A1 | |
| SCHEMBL30080532 | 0.74 | HSD17B10 (0.46) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL20577408 | 0.72 | PLD1 (0.54) | ALDH1A1HPGDHSD17B10PLD1 | |
| SCHEMBL22326 | 0.71 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDHSD17B10PLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1263751-C | Novel compounds | ASTRAZENECA AB (SE) | 2006-07-12 | — | — | CN | disclosed |
| CN-1541214-A | Novel compounds | — | 2004-10-27 | — | — | CN | disclosed |