Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 7/20 | 0.48 |
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455561 | 0.98 | MIF (0.54) | MIFHSD17B10TSHRTRPA1TP53 | |
| Paraben SCHEMBL6755103 | 0.90 | CA2 (0.59) | MIFHSD17B10TSHRTRPA1TP53 | |
| SCHEMBL6755096 | 0.84 | PRSS1 (0.53) | HSD17B10 | |
| SCHEMBL941258 | 0.83 | P2RY6 (0.50) | MIFHSD17B10CA2CA1P2RY6 | |
| SCHEMBL23481284 | 0.81 | HSD17B10 (0.49) | MIFHSD17B10TRPA1CA2CA1 | |
| SCHEMBL635606 | 0.80 | MIF (0.59) | MIFHSD17B10TRPA1CA2CA1 | |
| SCHEMBL3398682 | 0.80 | KDM4E (0.50) | MIFHSD17B10TRPA1CA2CA1 | |
| SCHEMBL3900460 | 0.79 | MIF (0.41) | MIFHSD17B10TSHRTP53CA2 | |
| SCHEMBL1308638 | 0.79 | NOS3 (0.53) | MIFHSD17B10CA2CA1P2RY6 | |
| SCHEMBL10576522 | 0.79 | P2RY6 (0.52) | MIFHSD17B10TSHRTRPA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1225654-A | Angiogenic inhibitory compounds | BIOMOLECULAR RES INST LTD (AU) | 1999-08-11 | — | — | CN | disclosed |
| CN-1225653-A | Antiviral linear polymer | BIOMOLECULAR RES INST LTD (AU) | 1999-08-11 | — | — | CN | disclosed |