Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 3/20 | 0.32 |
| ▸ | BRD7 | Q9NPI1 | 3/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | KLK1 | P06870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2761914 | 0.67 | TAAR1 (0.56) | MAPTTAAR1HTR2AHTR2C | |
| SCHEMBL27566802 | 0.65 | ALDH1A1 (0.56) | KDM4EALDH1A1LMNAMAPTNR4A1 | |
| SCHEMBL774974 | 0.64 | HTR2A (0.57) | KDM4EALDH1A1TAAR1HTR2AHTR2C | |
| SCHEMBL2386941 | 0.61 | ACHE (0.56) | KDM4EALDH1A1LMNAMAPTTAAR1 | |
| Hydrochloric Acid SCHEMBL857370 | 0.60 | ACHE (0.54) | KDM4EALDH1A1LMNAMAPTTAAR1 | |
| SCHEMBL27566803 | 0.60 | MAPT (0.38) | KDM4EALDH1A1LMNAMAPTNR4A1 | |
| SCHEMBL26133654 | 0.60 | HTR2A (0.50) | KDM4ETAAR1HTR2AHTR2C | |
| SCHEMBL23836672 | 0.59 | TAAR1 (0.60) | KDM4EALDH1A1MAPTTAAR1HTR2A | |
| SCHEMBL19882731 | 0.59 | POLB (0.48) | ALDH1A1MAPTTAAR1HTR2AHTR2C | |
| SCHEMBL11440396 | 0.58 | MAPT (0.57) | KDM4EALDH1A1LMNAMAPTNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1276790-A | Carboxamidothiazole derivs., preparation, pharmaceutical composition contg. them | SANOFI SA (FR) | 2000-12-13 | — | — | CN | disclosed |