Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688735 | 0.85 | MAPT (0.41) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL27566801 | 0.78 | ALDH1A1 (0.41) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL7681878 | 0.73 | ALDH1A1 (0.43) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL17386575 | 0.68 | MAPT (0.49) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8894861 | 0.65 | MEN1 (0.54) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL7386827 | 0.63 | NSD2 (0.43) | SMN1; SMN2ALDH1A1MAPK1KDM4ETSHR | |
| SCHEMBL25256788 | 0.63 | SMN1; SMN2 (0.44) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL2379547 | 0.62 | ALDH1A1 (0.56) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8896650 | 0.62 | ALDH1A1 (0.63) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL17407190 | 0.61 | RAB9A (0.45) | MAPTSMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1276790-A | Carboxamidothiazole derivs., preparation, pharmaceutical composition contg. them | SANOFI SA (FR) | 2000-12-13 | — | — | CN | disclosed |