Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17656461 | 0.78 | — | — | |
| SCHEMBL5906945 | 0.77 | PTPN1 (0.50) | PTPN1CHRM3LMNACHRM2CHRM4 | |
| SCHEMBL12905841 | 0.69 | PTPN1 (0.45) | PTPN1CHRM3LMNACHRM2CHRM4 | |
| SCHEMBL10036725 | 0.68 | PTPN1 (0.44) | PTPN1CHRM3LMNACHRM2CHRM4 | |
| SCHEMBL6858231 | 0.68 | PTPN1 (0.55) | PTPN1CHRM3LMNACHRM2CHRM4 | |
| SCHEMBL14614628 | 0.68 | PTPN1 (0.44) | PTPN1CHRM3LMNACHRM2CHRM4 | |
| SCHEMBL28822133 | 0.68 | CHRM3 (0.43) | PTPN1CHRM3LMNACHRM2CHRM4 | |
| SCHEMBL19852053 | 0.67 | CHRM3 (0.35) | PTPN1CHRM3LMNACHRM2CHRM4 | |
| SCHEMBL13153088 | 0.67 | NOS3 (0.46) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL15947267 | 0.67 | CHRM3 (0.35) | PTPN1CHRM3LMNACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1049501-A | AZABICYCLO QUINOLONE CARBOXYLIC ACIDS | PFIZER (US) | 1991-02-27 | — | — | CN | disclosed |