Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GGT1 | P19440 | 2/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461571 | 0.89 | KMT2A (0.54) | TLR2KMT2AMMP2MMP9ALDH1A1 | |
| SCHEMBL461572 | 0.89 | KMT2A (0.54) | TLR2KMT2AMMP2MMP9ALDH1A1 | |
| SCHEMBL1508827 | 0.83 | TLR2 (0.53) | TLR2POLBGGT1 | |
| SCHEMBL1508716 | 0.83 | TLR2 (0.53) | TLR2POLBGGT1 | |
| SCHEMBL27836700 | 0.83 | TLR2 (0.53) | TLR2POLBGGT1 | |
| SCHEMBL14394199 | 0.81 | KMT2A (0.45) | TLR2KMT2AMMP2MMP9ALDH1A1 | |
| SCHEMBL2250167 | 0.80 | L3MBTL1 (0.51) | KMT2AMMP2MMP9ALDH1A1 | |
| SCHEMBL2249541 | 0.78 | L3MBTL1 (0.50) | KMT2AMMP2MMP9ALDH1A1RAB9A | |
| SCHEMBL2251543 | 0.78 | FFAR1 (0.46) | KMT2AMMP2MMP9 | |
| Sulfotep SCHEMBL497489 | 0.78 | KMT2A (0.42) | TLR2KMT2AMMP2MMP9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308375-C | Lipid-polymer-conjugates compsns. | YAMANOUCHI EUROP BV (NL) | 2007-04-04 | — | — | CN | disclosed |
| CN-1271116-C | Lipid-polymer-conjugates | YAMANOUCHI EUROP BV (NL) | 2006-08-23 | — | — | CN | disclosed |
| CN-1602326-A | Lipid-polymer-conjugates | YAMANOUCHI EUROP BV (NL) | 2005-03-30 | — | — | CN | disclosed |
| CN-1520435-A | Lipid-polymer-conjugates compsns. | ֮��ŷ������˾ | 2004-08-11 | — | — | CN | disclosed |