Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 4/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461571 | 0.82 | KMT2A (0.54) | KMT2AALDH1A1RAB9ATLR2MMP2 | |
| SCHEMBL461572 | 0.82 | KMT2A (0.54) | KMT2AALDH1A1RAB9ATLR2MMP2 | |
| SCHEMBL27520105 | 0.78 | TLR2 (0.46) | KMT2AALDH1A1RAB9ATLR2MMP2 | |
| Sulfotep SCHEMBL11794973 | 0.76 | LMNA (0.43) | KMT2AALDH1A1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL14394199 | 0.74 | KMT2A (0.45) | KMT2AALDH1A1RAB9ATLR2MMP2 | |
| Sulfotep SCHEMBL11795269 | 0.74 | LMNA (0.42) | KMT2AALDH1A1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL2251543 | 0.74 | FFAR1 (0.46) | KMT2AMMP2MMP9MMEPDCD1 | |
| SCHEMBL2250167 | 0.73 | L3MBTL1 (0.51) | KMT2AALDH1A1MMP2MMP9MEN1 | |
| SCHEMBL2242522 | 0.73 | MMP2 (0.48) | ALDH1A1RAB9AMMP2MMP9 | |
| SCHEMBL2249541 | 0.72 | L3MBTL1 (0.50) | KMT2AALDH1A1RAB9AMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986553-B1 | U-SHAPED DISC-SHUNT AND DELIVERY DEVICE | ALEEVA MEDICAL INC (US) | 2016-03-30 | — | — | EP | claimed |
| US-8361007-B2 | U-shaped disc shunt and delivery device | ALEEVA MEDICAL INC. (US) | 2013-01-29 | — | — | US | claimed |
| US-20090024071-A1 | U-Shaped Disc Shunt and Delivery Device | YEUNG JEFFREY E | 2009-01-22 | — | — | US | claimed |
| US-20070169911-A1 | U-shaped disc shunt and delivery device | ALEEVA MEDICAL INC., A DELAWARE CORPORATION | 2007-07-26 | — | — | US | claimed |
| US-20070142791-A1 | U-shaped disc shunt and delivery device | ALEEVE MEDICAL INC. A DELAWARE CORPORATION | 2007-06-21 | — | — | US | claimed |
| EP-1986553-B1 | U-SHAPED DISC-SHUNT AND DELIVERY DEVICE | ALEEVA MEDICAL INC (US) | 2016-03-30 | — | — | EP | disclosed |
| US-8361007-B2 | U-shaped disc shunt and delivery device | ALEEVA MEDICAL INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-8105344-B2 | Spooled filament to repair tissue | ALEEVA MEDICAL INC. (US) | 2012-01-31 | — | — | US | disclosed |
| CN-101378701-B | U-Shaped Disc Bypass and Delivery Device | ALEEVA MEDICAL INC. (US) | 2011-12-07 | — | — | CN | disclosed |
| US-20100030241-A1 | Spooled filament to repair tissue | YEUNG JEFFREY E | 2010-02-04 | — | — | US | disclosed |
| CN-101378701-A | U-Shaped Disc Bypass and Delivery Device | YEUNG JEFFREY E (US) | 2009-03-04 | — | — | CN | disclosed |
| US-20090024071-A1 | U-Shaped Disc Shunt and Delivery Device | YEUNG JEFFREY E | 2009-01-22 | — | — | US | disclosed |
| EP-1986553-A2 | U-SHAPED DISC-SHUNT AND DELIVERY DEVICE | Aleeva Medical, Inc. (US) | 2008-11-05 | — | — | EP | disclosed |
| WO-2008013869-A2 | SPOOLED FILAMENT TO REPAIR TISSUE | YEUNG FEFFREY E (US) | 2008-01-31 | — | — | WO | disclosed |
| WO-2007089947-A2 | U-SHAPED DISC-SHUNT AND DELIVERY DEVICE | ALEEVA MEDICAL INC. (US) | 2007-08-09 | — | — | WO | disclosed |
| US-20070169911-A1 | U-shaped disc shunt and delivery device | ALEEVA MEDICAL INC., A DELAWARE CORPORATION | 2007-07-26 | — | — | US | disclosed |
| US-20070142791-A1 | U-shaped disc shunt and delivery device | ALEEVE MEDICAL INC. A DELAWARE CORPORATION | 2007-06-21 | — | — | US | disclosed |