Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 2/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1817604 | 0.76 | NOS3 (0.48) | NOS3NOS1NOS2NAPRTSMN1; SMN2 | |
| SCHEMBL283791 | 0.71 | NOS3 (0.52) | NOS3NOS1NOS2NAPRTSMN1; SMN2 | |
| SCHEMBL20424997 | 0.68 | NOS3 (0.48) | NOS3NOS1NOS2NAPRTSMN1; SMN2 | |
| SCHEMBL183159 | 0.67 | NOS3 (0.46) | NOS3NOS1NOS2NAPRTL3MBTL1 | |
| SCHEMBL10726947 | 0.67 | NOS3 (0.46) | NOS3NOS1NOS2NAPRTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29857654 | 0.66 | NOS3 (0.45) | NOS3NOS1NOS2NAPRTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL28202486 | 0.66 | NOS3 (0.45) | NOS3NOS1NOS2NAPRTL3MBTL1 | |
| SCHEMBL20686388 | 0.66 | NOS2 (0.45) | NOS3NOS1NOS2NAPRTSMN1; SMN2 | |
| SCHEMBL25736998 | 0.66 | NOS2 (0.45) | NOS3NOS1NOS2NAPRTSMN1; SMN2 | |
| SCHEMBL2085704 | 0.64 | P2RX7 (0.38) | NOS3NOS1NOS2SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1523015-A | 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines | �Ʒ� | 2004-08-25 | — | — | CN | disclosed |
| CN-1515554-A | Intermediate compound for producing 2-amino-6-(2-substituted-4-phenoxy) substituted pyridine compound | �Ʒ� | 2004-07-28 | — | — | CN | disclosed |
| CN-1246848-A | 2-amino-6- (2-substituted-4-phenoxy) -substituted pyridines | PFIZER PROD INC (US) | 2000-03-08 | — | — | CN | disclosed |