Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | CEL | P19835 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11675755 | 0.85 | NUDT1 (0.45) | NUDT1BACE1SIGMAR1TMEM97EBP | |
| SCHEMBL11799765 | 0.84 | NUDT1 (0.44) | NUDT1BACE1SIGMAR1TMEM97EBP | |
| SCHEMBL11674401 | 0.84 | BACE1 (0.48) | NUDT1BACE1SIGMAR1TMEM97EBP | |
| SCHEMBL11674174 | 0.81 | SIGMAR1 (0.43) | NUDT1BACE1SIGMAR1TMEM97EBP | |
| SCHEMBL8330793 | 0.81 | NUDT1 (0.52) | NUDT1BACE1SIGMAR1TMEM97EBP | |
| SCHEMBL11675518 | 0.80 | MEN1 (0.46) | NUDT1BACE1SIGMAR1TMEM97EBP | |
| SCHEMBL10829892 | 0.80 | SIGMAR1 (0.48) | NUDT1BACE1SIGMAR1TMEM97EBP | |
| SCHEMBL3900326 | 0.80 | NUDT1 (0.43) | NUDT1BACE1SIGMAR1TMEM97EBP | |
| SCHEMBL11673726 | 0.79 | NUDT1 (0.43) | NUDT1BACE1SIGMAR1TMEM97EBP | |
| SCHEMBL11674093 | 0.79 | PTGDR2 (0.49) | NUDT1BACE1THRBPTGDRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1226825-A | Use of amines to produce drugs for preventing tumour cell proliferation | SANOFI SA (FR) | 1999-08-25 | — | — | CN | claimed |