Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29290942 | 0.83 | SMN1; SMN2 (0.41) | POLBSMN1; SMN2KDM4EEP300KAT2B | |
| SCHEMBL27522973 | 0.83 | POLB (0.35) | POLBSMN1; SMN2KDM4EEP300KAT2B | |
| SCHEMBL27520393 | 0.81 | KDM4E (0.34) | POLBSMN1; SMN2KDM4EEP300KAT2B | |
| SCHEMBL29290951 | 0.80 | POLB (0.35) | POLBSMN1; SMN2KDM4EEP300KAT2B | |
| SCHEMBL27504274 | 0.75 | POLB (0.37) | POLBSMN1; SMN2KDM4EEP300KAT2B | |
| SCHEMBL29290947 | 0.69 | SMN1; SMN2 (0.41) | POLBSMN1; SMN2KDM4EEP300KAT2B | |
| SCHEMBL27502491 | 0.67 | KDM4E (0.34) | POLBSMN1; SMN2KDM4EALDH1A1TSHR | |
| SCHEMBL28565280 | 0.63 | SMN1; SMN2 (0.34) | POLBSMN1; SMN2KDM4EEP300KAT2B | |
| SCHEMBL18885095 | 0.63 | CRBN (0.38) | SMN1; SMN2KDM4EEP300KAT2BALDH1A1 | |
| SCHEMBL951241 | 0.62 | SMN1; SMN2 (0.39) | POLBSMN1; SMN2KDM4EEP300KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678854-A | A kind of method that manganese catalyzes and synthesizes pyrido [1,2-a] indoles -6 (1H) -one class compound | 陕西师范大学 | 2019-04-26 | — | — | CN | disclosed |