Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27537341 | 0.78 | GAA (0.39) | MEN1GAAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL11027264 | 0.78 | GAA (0.48) | MEN1GAAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL6440708 | 0.77 | GAA (0.45) | MEN1GAAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL14890742 | 0.73 | TSHR (0.51) | MEN1KMT2ASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL8192518 | 0.73 | L3MBTL1 (0.46) | MEN1GAAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL8203981 | 0.73 | L3MBTL1 (0.46) | MEN1GAAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL16118686 | 0.72 | HSD17B10 (0.49) | TSHRL3MBTL1TDP1ALDH1A1HSD17B10 | |
| SCHEMBL30291518 | 0.72 | SMN1; SMN2 (0.40) | MEN1GAAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL5665937 | 0.72 | CYP1A2 (0.45) | MEN1GAAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL5665495 | 0.70 | HTT (0.53) | SMN1; SMN2TSHRALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1226888-A | Fluorinated 1,4-disubstituted piperidine derivatives | BANYU PHARMA CO LTD (JP) | 1999-08-25 | — | — | CN | claimed |
| CN-1226888-A | Fluorinated 1,4-disubstituted piperidine derivatives | BANYU PHARMA CO LTD (JP) | 1999-08-25 | — | — | CN | disclosed |