Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CTRC | Q99895 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 5/20 | 0.56 |
| ▸ | CTSS | P25774 | 2/20 | 0.56 |
| ▸ | CTSV | O60911 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | MMP7 | P09237 | 1/20 | 0.56 |
| ▸ | GPR132 | Q9UNW8 | 4/20 | 0.56 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.55 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415738 | 1.00 | ECE1 (0.64) | ECE1LMNACTRCCTSLCTSS | |
| SCHEMBL201265 | 0.94 | ECE1 (0.55) | ECE1LMNACTRCCTSLCTSS | |
| SCHEMBL27518028 | 0.94 | ECE1 (0.55) | ECE1LMNACTRCCTSLCTSS | |
| SCHEMBL202770 | 0.92 | CTSL (0.60) | ECE1LMNACTRCCTSLCTSS | |
| SCHEMBL27547470 | 0.92 | CTSL (0.60) | ECE1LMNACTRCCTSLCTSS | |
| SCHEMBL15869689 | 0.89 | ECE1 (0.62) | ECE1LMNACTRCCTSLCTSS | |
| SCHEMBL3497405 | 0.88 | GPR132 (0.69) | ECE1LMNACTRCGPR132CMKLR2 | |
| SCHEMBL30037998 | 0.88 | GPR132 (0.69) | ECE1LMNACTRCGPR132CMKLR2 | |
| SCHEMBL2229201 | 0.88 | GPR132 (0.69) | ECE1LMNACTRCGPR132CMKLR2 | |
| SCHEMBL7417163 | 0.86 | CTSL (0.68) | CTSLCTSSCTSBHDAC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1265647-A | Acyclic metalloprotease inhibitors | PROCTER & GAMBLE (US) | 2000-09-06 | — | — | CN | disclosed |