Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.47 |
| ▸ | GALR2 | O43603 | 3/20 | 0.47 |
| ▸ | GALR1 | P47211 | 3/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27345375 | 0.84 | MEN1 (0.69) | MEN1KMT2ANPC1RAB9AGALR2 | |
| SCHEMBL12488156 | 0.83 | GALR2 (0.67) | MEN1KMT2ANPC1RAB9AMAP2K7 | |
| SCHEMBL27339277 | 0.77 | EGFR (0.45) | MEN1KMT2ANPC1RAB9ATUBB4A | |
| SCHEMBL27330845 | 0.77 | TNNI3K (0.54) | EGFRERBB3TNNI3K | |
| SCHEMBL27323499 | 0.77 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9AEGFR | |
| SCHEMBL12481653 | 0.76 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9AEGFR | |
| SCHEMBL27339286 | 0.76 | PRCP (0.49) | MEN1KMT2ANPC1RAB9ATUBB4A | |
| SCHEMBL374361 | 0.75 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9ATUBB4A | |
| SCHEMBL8317346 | 0.75 | EGFR (0.51) | EGFR | |
| SCHEMBL8801487 | 0.75 | EGFR (0.50) | MEN1KMT2ANPC1RAB9ATUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1047778-C | Pyrimido [5-4-d] pyrimidines, drugs containing these compounds, their use and process for preparing them | THOMAE GMBH DR K (DE) | 1999-12-29 | — | — | CN | disclosed |