Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.33 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.33 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.33 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.33 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2092777 | 0.85 | MEN1 (0.44) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL2098152 | 0.80 | KDM4E (0.31) | KDM4E | |
| SCHEMBL2094702 | 0.78 | CA2 (0.47) | ALDH1A1CYP1A1CYP1B1CYP1A2L3MBTL1 | |
| SCHEMBL2753977 | 0.78 | KDM4E (0.31) | KDM4E | |
| SCHEMBL2751404 | 0.77 | KCNH2 (0.38) | — | |
| SCHEMBL2751578 | 0.77 | CA12 (0.50) | ALDH1A1CYP1A1CYP1B1CYP1A2CYP2E1 | |
| SCHEMBL2751899 | 0.77 | CA12 (0.50) | ALDH1A1CYP1A1CYP1B1CYP1A2CYP2E1 | |
| SCHEMBL2095700 | 0.76 | MEN1 (0.53) | ALDH1A1CYP2C9KDM4EMEN1KMT2A | |
| SCHEMBL2749440 | 0.74 | CYP1B1 (0.50) | ALDH1A1CYP1A1CYP1B1CYP1A2CYP2E1 | |
| SCHEMBL2752261 | 0.74 | HAO1 (0.47) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541764-B | Pyrimidylmethyl-sulfonamide compounds useful as fungicides and against arthropods | BASF SE | 2012-10-10 | — | — | CN | disclosed |
| US-8178540-B2 | Pyrimidylmethyl-sulfonamide compounds | BASF SE (DE) | 2012-05-15 | — | — | US | disclosed |
| US-20100077512-A1 | Pyridazin-4-ylmethyl-sulfonamides used as Fungicides and Against Arthropods | BASF SE (DE) | 2010-03-25 | — | — | US | disclosed |
| US-20100069243-A1 | Pyrimidylmethyl-Sulfonamide Compounds | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069243-A1 | Pyrimidylmethyl-Sulfonamide Compounds | TPMT, NISCH, PPA1 | ALDH1A1 1588/4885CYP1A1 1616/4885CYP1B1 1464/4885 |
| US-20100077512-A1 | Pyridazin-4-ylmethyl-sulfonamides used as Fungicides and Against Arthropods | PIR, PRDX4, PRDX2 | ALDH1A1 2607/4885CYP1A1 599/4885CYP1B1 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.