Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP4B1 | P13584 | 3/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 3/20 | 0.42 |
| ▸ | CYP2A7 | P20853 | 3/20 | 0.42 |
| ▸ | CYP3A7 | P24462 | 3/20 | 0.42 |
| ▸ | CYP2F1 | P24903 | 3/20 | 0.42 |
| ▸ | CYP2C18 | P33260 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 3/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.42 |
| ▸ | CYP4F8 | P98187 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500272 | 0.83 | CYP19A1 (0.49) | ALDH1A1NPC1RAB9AADORA3KDM4E | |
| SCHEMBL679068 | 0.81 | NPC1 (0.50) | CYP1B1CYP1A1ALDH1A1NPC1RAB9A | |
| SCHEMBL2752051 | 0.74 | ALDH1A1 (0.41) | CYP1B1CYP1A1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL2095558 | 0.74 | PKM (0.47) | ALDH1A1NPC1RAB9AADORA3KDM4E | |
| SCHEMBL17626204 | 0.73 | MAPT (0.42) | ALDH1A1NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL29042383 | 0.73 | CYP19A1 (0.43) | CYP3A4GAK | |
| SCHEMBL2750142 | 0.71 | KMT2A (0.48) | CYP1B1CYP1A1ALDH1A1NPC1ADORA3 | |
| SCHEMBL1435812 | 0.71 | CYP1A1 (0.57) | CYP1B1CYP1A1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL2752780 | 0.70 | GRM5 (0.41) | CYP1A2 | |
| SCHEMBL17626136 | 0.70 | ALDH1A1 (0.57) | ALDH1A1NPC1RAB9AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178540-B2 | Pyrimidylmethyl-sulfonamide compounds | BASF SE (DE) | 2012-05-15 | — | — | US | disclosed |
| US-20100077512-A1 | Pyridazin-4-ylmethyl-sulfonamides used as Fungicides and Against Arthropods | BASF SE (DE) | 2010-03-25 | — | — | US | disclosed |
| US-20100069243-A1 | Pyrimidylmethyl-Sulfonamide Compounds | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069243-A1 | Pyrimidylmethyl-Sulfonamide Compounds | TPMT, NISCH, PPA1 | CYP1B1 1464/4885CYP1A1 1616/4885CYP1A2 1087/4885 |
| US-20100077512-A1 | Pyridazin-4-ylmethyl-sulfonamides used as Fungicides and Against Arthropods | PIR, PRDX4, PRDX2 | CYP1B1 622/4885CYP1A1 599/4885CYP1A2 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.