Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 5/20 | 0.32 |
| ▸ | NOS3 | P29474 | 3/20 | 0.32 |
| ▸ | NOS2 | P35228 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8173271 | 0.73 | NOS1 (0.33) | NOS1NOS3NOS2 | |
| SCHEMBL4938 | 0.71 | NOS1 (0.32) | NOS1NOS3NOS2 | |
| SCHEMBL2332914 | 0.62 | NOS1 (0.33) | NOS1NOS3NOS2 | |
| SCHEMBL1670886 | 0.59 | NOS1 (0.33) | NOS1NOS3NOS2 | |
| SCHEMBL29383163 | 0.59 | NOS1 (0.33) | NOS1NOS3NOS2 | |
| SCHEMBL7465174 | 0.57 | NOS1 (0.32) | NOS1NOS3NOS2 | |
| SCHEMBL20991139 | 0.55 | NOS1 (0.44) | NOS1NOS3NOS2 | |
| SCHEMBL4409993 | 0.54 | MEN1 (0.32) | — | |
| SCHEMBL28886119 | 0.54 | NOS1 (0.42) | NOS1NOS3NOS2 | |
| SCHEMBL8069320 | 0.52 | MEN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1837231-A | Immunomodulatory steroids, in particular the hemihydrate of 16, alpha-bromoepiandrosterone | HOLLIS EDEN PHARMACEUTICALS (US) | 2006-09-27 | — | — | CN | disclosed |
| CN-1243767-C | Immunomodulatory steroids, in particular hemihydrate of 16 alpha-bromoepiandrosterone | HOLLIS EDEN PHARMACEUTICALS (US) | 2006-03-01 | — | — | CN | disclosed |
| CN-1355809-A | Immunomodulatory steroids, in particular hemihydrate of 16 alpha-bromoepiandrosterone | HOLLIS EDEN PHARMACEUTICALS (US) | 2002-06-26 | — | — | CN | disclosed |