Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 2/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486117 | 0.91 | CYP1A2 (0.42) | CNR2CYP3A4TSHRCYP1A2CYP2D6 | |
| SCHEMBL8554152 | 0.79 | POLB (0.41) | CNR2POLBRAB9AKDM4EALDH1A1 | |
| SCHEMBL8554981 | 0.75 | POLB (0.42) | CNR2POLBRAB9AKDM4EALDH1A1 | |
| SCHEMBL8592569 | 0.75 | POLB (0.39) | CNR2POLBRAB9AKDM4EALDH1A1 | |
| SCHEMBL8813165 | 0.71 | BACE1 (0.35) | CNR2POLBRAB9AKDM4EALDH1A1 | |
| SCHEMBL8593434 | 0.71 | KCNK3 (0.37) | CNR2POLBRAB9AKDM4EALDH1A1 | |
| SCHEMBL8593535 | 0.70 | CYP1A2 (0.41) | CYP3A4TSHRCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8596274 | 0.69 | GPR88 (0.34) | POLBRAB9AKDM4EALDH1A1GPR88 | |
| SCHEMBL8594406 | 0.66 | CYP1A2 (0.39) | CYP3A4TSHRCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7010983 | 0.64 | FAAH (0.46) | CNR2KDM4EALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1197452-A | Azetidinone derivatives for treatment of atherosclerosis | SMITHKLINE BEECHAM PLC (GB) | 1998-10-28 | — | — | CN | claimed |