SCHEMBL27520787

SCHEMBL27520787

COc1cc(C=CC(=O)OC/C=C/c2ccc(O)c(OC)c2)ccc1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.76
EPHX2 P34913 1/20 0.70
MET P08581 8/20 0.67
CA12 O43570 5/20 0.67
CA4 P22748 5/20 0.67
CA6 P23280 5/20 0.67
CA5A P35218 5/20 0.67
CA7 P43166 5/20 0.67
CA9 Q16790 5/20 0.67
CA14 Q9ULX7 5/20 0.67
CA5B Q9Y2D0 5/20 0.67
CYP2D6 P10635 3/20 0.66
CYP2C9 P11712 2/20 0.66
TSHR P16473 2/20 0.66
HSD17B10 Q99714 2/20 0.66
CYP1A2 P05177 2/20 0.66
ALOX5 P09917 2/20 0.66
NFKB1 P19838 2/20 0.66
HSD11B1 P28845 2/20 0.66
STAT3 P40763 2/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10054940 1.00 MAOB (0.76) MAOBEPHX2METCA12CA4
SCHEMBL434930 1.00 MAOB (0.76) MAOBEPHX2METCA12CA4
SCHEMBL29577685 0.96 MAOB (0.70) MAOBEPHX2METCA12CA4
SCHEMBL15019742 0.96 MAOB (0.70) MAOBEPHX2METCA12CA4
SCHEMBL17866313 0.95 MET (0.72) MAOBEPHX2METCA12CA4
SCHEMBL20515821 0.95 MET (0.69) MAOBEPHX2METCA12CA4
SCHEMBL20515824 0.95 MET (0.69) MAOBEPHX2METCA12CA4
SCHEMBL20515823 0.95 MET (0.69) MAOBEPHX2METCA12CA4
SCHEMBL13499768 0.95 MET (0.69) MAOBEPHX2METCA12CA4
SCHEMBL10054939 0.95 MET (0.72) MAOBEPHX2METCA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105709169-A Ointment for treating wind-damp pain of neck, shoulders, waist and legs 徐利华 2016-06-29 CN disclosed
CN-102824497-B Bone rheumatism pain relieving liquid and preparation method thereof GANSU PROVINCE HOSPITAL OF TRADITIONAL CHINESE MEDICINE 2014-11-05 CN disclosed
CN-102824393-B Pharmaceutical composition for dispelling wind, relieving pain, dispelling cold, and removing dampness and preparation method thereof GANSU PROVINCE HOSPITAL OF TRADITIONAL CHINESE MEDICINE 2014-04-16 CN disclosed
CN-102824497-A Bone rheumatism pain relieving liquid and preparation method thereof GANSU PROVINCE HOSPITAL OF TRADITIONAL CHINESE MEDICINE 2012-12-19 CN disclosed
CN-102824393-A Pharmaceutical composition for dispelling wind, relieving pain, dispelling cold, and removing dampness and preparation method thereof GANSU PROVINCE HOSPITAL OF TRADITIONAL CHINESE MEDICINE 2012-12-19 CN disclosed
CN-1278679-C Application of coniferyl ferulate in anticancer medicine DALIAN CHEMICAL PHYSICS INST (CN) 2006-10-11 CN disclosed
CN-1608616-A Application of coniferyl ferulate in anticancer medicine DALIAN CHEMICAL PHYSICS INST (CN) 2005-04-27 CN disclosed