Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 11/20 | 0.72 |
| ▸ | MAOB | P27338 | 2/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 3/20 | 0.62 |
| ▸ | CA4 | P22748 | 3/20 | 0.62 |
| ▸ | CA6 | P23280 | 3/20 | 0.62 |
| ▸ | CA5A | P35218 | 3/20 | 0.62 |
| ▸ | CA7 | P43166 | 3/20 | 0.62 |
| ▸ | CA9 | Q16790 | 3/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.62 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.60 |
| ▸ | STAT3 | P40763 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10054939 | 1.00 | MET (0.72) | METMAOBEPHX2CA12CA4 | |
| SCHEMBL434930 | 0.95 | MAOB (0.76) | METMAOBEPHX2CA12CA4 | |
| SCHEMBL27520787 | 0.95 | MAOB (0.76) | METMAOBEPHX2CA12CA4 | |
| SCHEMBL10054940 | 0.95 | MAOB (0.76) | METMAOBEPHX2CA12CA4 | |
| SCHEMBL29578252 | 0.94 | MET (0.65) | METMAOBEPHX2ALOX5APP | |
| SCHEMBL29577685 | 0.91 | MAOB (0.70) | METMAOBEPHX2CA12CA4 | |
| SCHEMBL15019742 | 0.91 | MAOB (0.70) | METMAOBEPHX2CA12CA4 | |
| SCHEMBL29848508 | 0.91 | MET (0.70) | METCYP2D6ALOX5CYP2C9CYP1A2 | |
| SCHEMBL432405 | 0.90 | MET (0.69) | METMAOBEPHX2CA12CA4 | |
| SCHEMBL20515821 | 0.90 | MET (0.69) | METMAOBEPHX2CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11414372-B2 | Methods for detecting and determining levels of monolignol ester conjugates incorporated into lignin and compounds relating thereto | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2022-08-16 | — | — | US | disclosed |
| US-20190152890-A1 | METHODS FOR DETECTING AND DETERMINING LEVELS OF MONOLIGNOL ESTER CONJUGATES INCORPORATED INTO LIGNIN AND COMPOUNDS RELATING THERETO | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-05-23 | — | — | US | disclosed |
| US-10227287-B2 | Method for detecting and determining levels of monolignol ester conjugates incorporated into lignin and compounds relating thereto | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-03-12 | — | — | US | disclosed |
| US-20160187345-A1 | METHODS FOR DETECTING AND DETERMINING LEVELS OF MONOLIGNOL ESTER CONJUGATES INCORPORATED INTO LIGNIN AND COMPOUNDS RELATING THERETO | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190152890-A1 | METHODS FOR DETECTING AND DETERMINING LEVELS OF MONOLIGNOL ESTER CONJUGATES INCORPORATED INTO LIGNIN AND COMPOUNDS RELATING THERETO | HAAO, LPO, GUSB | MET 3250/4885MAOB 686/4885EPHX2 122/4885 |
| US-10227287-B2 | Method for detecting and determining levels of monolignol ester conjugates incorporated into lignin and compounds relating thereto | HAAO, LPO, LANCL1 | MET 2953/4885MAOB 632/4885EPHX2 145/4885 |
| US-11414372-B2 | Methods for detecting and determining levels of monolignol ester conjugates incorporated into lignin and compounds relating thereto | HAAO, AOX1, LPO | MET 2886/4885MAOB 556/4885EPHX2 268/4885 |
| US-20160187345-A1 | METHODS FOR DETECTING AND DETERMINING LEVELS OF MONOLIGNOL ESTER CONJUGATES INCORPORATED INTO LIGNIN AND COMPOUNDS RELATING THERETO | HAAO, LPO, GUSB | MET 3250/4885MAOB 686/4885EPHX2 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.