SCHEMBL10054940

SCHEMBL10054940

COc1cc(/C=C/COC(=O)/C=C/c2ccc(O)c(OC)c2)ccc1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.76
EPHX2 P34913 1/20 0.70
MET P08581 8/20 0.67
CA12 O43570 5/20 0.67
CA4 P22748 5/20 0.67
CA6 P23280 5/20 0.67
CA5A P35218 5/20 0.67
CA7 P43166 5/20 0.67
CA9 Q16790 5/20 0.67
CA14 Q9ULX7 5/20 0.67
CA5B Q9Y2D0 5/20 0.67
CYP2D6 P10635 3/20 0.66
CYP2C9 P11712 2/20 0.66
TSHR P16473 2/20 0.66
HSD17B10 Q99714 2/20 0.66
CYP1A2 P05177 2/20 0.66
ALOX5 P09917 2/20 0.66
NFKB1 P19838 2/20 0.66
HSD11B1 P28845 2/20 0.66
STAT3 P40763 2/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27520787 1.00 MAOB (0.76) MAOBEPHX2METCA12CA4
SCHEMBL434930 1.00 MAOB (0.76) MAOBEPHX2METCA12CA4
SCHEMBL29577685 0.96 MAOB (0.70) MAOBEPHX2METCA12CA4
SCHEMBL15019742 0.96 MAOB (0.70) MAOBEPHX2METCA12CA4
SCHEMBL17866313 0.95 MET (0.72) MAOBEPHX2METCA12CA4
SCHEMBL20515821 0.95 MET (0.69) MAOBEPHX2METCA12CA4
SCHEMBL20515824 0.95 MET (0.69) MAOBEPHX2METCA12CA4
SCHEMBL20515823 0.95 MET (0.69) MAOBEPHX2METCA12CA4
SCHEMBL13499768 0.95 MET (0.69) MAOBEPHX2METCA12CA4
SCHEMBL10054939 0.95 MET (0.72) MAOBEPHX2METCA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807876-B2 P-coumaroyl-CoA:monolignol transferases WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-11-07 US disclosed
US-11807875-B2 Feruloyl-CoA:monolignol transferases WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-11-07 US disclosed
US-11807875-B2 Feruloyl-CoA:monolignol transferases WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-11-07 US disclosed
US-11807876-B2 P-coumaroyl-CoA:monolignol transferases WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-11-07 US disclosed
CN-111617072-B Hyperuricemia medicine composition and medicine for treating hyperuricemia 苏州凯祥生物科技有限公司 2023-06-20 CN disclosed
CN-111617071-B Hyperuricemia medicine composition and medicine for treating hyperuricemia 苏州凯祥生物科技有限公司 2023-05-23 CN disclosed
CN-115531485-A Pharmaceutical composition for treating chronic gastritis and preparation method thereof 陕西中医药大学 2022-12-30 CN disclosed
US-11414372-B2 Methods for detecting and determining levels of monolignol ester conjugates incorporated into lignin and compounds relating thereto WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2022-08-16 US disclosed
US-11326178-B2 P-coumaroyl-CoA:monolignol transferase WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2022-05-10 US disclosed
US-20220002744-A1 BAHD ACYLTRANSFERASES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2022-01-06 US disclosed
US-20130219547-A1 FERULOYL-CoA:MONOLIGNOL TRANSFERASE BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2013-08-22 US disclosed
US-20130219547-A1 FERULOYL-CoA:MONOLIGNOL TRANSFERASE BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2013-08-22 US disclosed
US-20130203973-A1 FERULOYL-CoA:MONOLIGNOL TRANSFERASE ENERGY, UNITED STATES DEPARTMENT OF 2013-08-08 US disclosed
US-20130203973-A1 FERULOYL-CoA:MONOLIGNOL TRANSFERASE ENERGY, UNITED STATES DEPARTMENT OF 2013-08-08 US disclosed
WO-2013090814-A2 p-Coumaroyl-CoA:Monolignol Transferase BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2013-06-20 WO disclosed
WO-2013052660-A1 HIBISCUS CANNABINUS FERULOYL-COA:MONOLIGNOL TRANSFERASE BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2013-04-11 WO disclosed
WO-2012012741-A1 FERULOYL-CoA:MONOLIGNOL TRANSFERASE BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2012-01-26 WO disclosed
WO-2012012698-A1 FERULOYL-CoA:MONOLIGNOL TRANSFERASE BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2012-01-26 WO disclosed
US-7482027-B2 Composition for the prevention or treatment of diseases associated with angiogenesis ANGIOLAB, INC. (KR) 2009-01-27 US disclosed
US-7482027-B2 Composition for the prevention or treatment of diseases associated with angiogenesis ANGIOLAB, INC. (KR) 2009-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130203973-A1 FERULOYL-CoA:MONOLIGNOL TRANSFERASE COASY, FDFT1, FER MAOB 1902/4885EPHX2 2909/4885MET 1999/4885
US-11414372-B2 Methods for detecting and determining levels of monolignol ester conjugates incorporated into lignin and compounds relating thereto HAAO, AOX1, LPO MAOB 556/4885EPHX2 268/4885MET 2886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.