Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 7/20 | 0.38 |
| ▸ | CNR2 | P34972 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27525665 | 0.80 | CNR2 (0.52) | CNR1CNR2ALDH1A1KDM4E | |
| SCHEMBL27550785 | 0.79 | CNR2 (0.43) | SERPINE1CNR1CNR2MCL1 | |
| SCHEMBL27525669 | 0.78 | CNR2 (0.55) | CNR1CNR2 | |
| SCHEMBL27550777 | 0.78 | CNR2 (0.55) | CNR1CNR2 | |
| SCHEMBL28540708 | 0.71 | KMT2A (0.34) | KMT2AALDH1A1POLBRXFP1 | |
| SCHEMBL27683832 | 0.70 | ATM (0.42) | CNR1CNR2 | |
| SCHEMBL16344098 | 0.68 | KAT2B (0.49) | KMT2AKAT2BALDH1A1KDM4EGAA | |
| SCHEMBL3721317 | 0.67 | KMT2A (0.54) | KMT2AKAT2BALDH1A1KDM4ECREBBP | |
| SCHEMBL28215959 | 0.66 | L3MBTL1 (0.66) | CNR1CNR2KMT2AALDH1A1KDM4E | |
| SCHEMBL7864455 | 0.66 | BCAT2 (0.59) | KMT2AALDH1A1GAANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1292694-A | New use | ASTRA ZENECA AKTIEBOLAG (SE) | 2001-04-25 | — | — | CN | disclosed |