SCHEMBL7759867

SCHEMBL7759867

O=C(O)c1ccccc1Cc1ccc(CO)cc1

nearest known ligand 0.74

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.74
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
CA9 Q16790 1/20 0.59
FOLH1 Q04609 2/20 0.55
PTPN1 P18031 5/20 0.49
PTPN2 P17706 1/20 0.47
PTPN6 P29350 1/20 0.47
ALDH1A1 P00352 1/20 0.46
ALOX15 P16050 1/20 0.46
HNF4A P41235 1/20 0.46
CYP2C9 P11712 1/20 0.45
HIF1A Q16665 1/20 0.45
LMNA P02545 1/20 0.45
GAA P10253 1/20 0.45
HPGD P15428 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
APEX1 P27695 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzyl Alcohol SCHEMBL5488535 0.96 TSHR (0.69) TSHRCA1CA2CA9FOLH1
SCHEMBL23003 0.88 TSHR (0.79) TSHRCA1CA2CA9FOLH1
Ethylene Glycol SCHEMBL1817402 0.87 TSHR (0.71) TSHRCA1CA2CA9FOLH1
Ammonia Solution, Strong SCHEMBL27527756 0.86 TSHR (0.76) TSHRCA1CA2CA9FOLH1
SCHEMBL28370887 0.86 TSHR (0.76) TSHRCA1CA2CA9FOLH1
SCHEMBL69041 0.85 TSHR (1.00) TSHRCA1CA2CA9FOLH1
SCHEMBL29580520 0.85 TSHR (0.74) TSHRCA1CA2CA9FOLH1
SCHEMBL2292722 0.85 TSHR (0.74) TSHRCA1CA2CA9FOLH1
SCHEMBL4908158 0.84 TSHR (0.72) TSHRCA1CA2CA9FOLH1
SCHEMBL4872353 0.84 TSHR (0.72) TSHRCA1CA2CA9FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0778157-B1 A thermal recording medium JUJO PAPER CO LTD (JP) 2001-04-04 EP disclosed
US-5811368-A BASIC LEUCO DYE, PHENOLIC COLOR DEVELOPER; IMPROVED STABILITY TO PLASTICIZERS NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1998-09-22 US disclosed
EP-0778157-A2 A thermal recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-06-11 EP disclosed