Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL29974267 | 0.93 | TSHR (0.86) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL23003 | 0.88 | TSHR (0.79) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL6030710 | 0.88 | TSHR (0.78) | TSHRCA1CA2CA9FOLH1 | |
| Ammonia Solution, Strong SCHEMBL27527756 | 0.86 | TSHR (0.76) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL28370887 | 0.86 | TSHR (0.76) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL29580520 | 0.85 | TSHR (0.74) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL7759867 | 0.85 | TSHR (0.74) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL2292722 | 0.85 | TSHR (0.74) | TSHRCA1CA2CA9FOLH1 | |
| SCHEMBL5567652 | 0.84 | TSHR (0.71) | TSHRCA1CA2CA9SRD5A2 | |
| SCHEMBL16950095 | 0.84 | TSHR (0.72) | TSHRCA1CA2CA9FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58194837-A | — | — | None | — | — | JP | disclosed |
| EP-1664798-B1 | NON-PEPTIDE AGONISTS AND ANTAGONISTS OF ADRENOMEDULLIN AND GASTRIN RELEASING PEPTIDE | US GOV HEALTH & HUMAN SERV (US) | 2013-05-22 | — | — | EP | disclosed |
| US-8420579-B2 | polytetrafluoroethylene, molybdenum disulfide or graphite as lubricant; a substrate containing polyamideimide resin and organic onium hydroxide compound modified sodium mica or sodium montmorillonite; n-methyl-2-pyrrolidone and xylene solvent; coating slilding surface, removing solvent | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20120232107-A1 | NON-PEPTIDE ANTAGONISTS OF GASTRIN RELEASING PEPTIDE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH | 2012-09-13 | — | — | US | disclosed |
| US-20120232107-A1 | NON-PEPTIDE ANTAGONISTS OF GASTRIN RELEASING PEPTIDE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH | 2012-09-13 | — | — | US | disclosed |
| EP-2479203-A1 | AROMATIC POLYESTER | Muroran Institute of Technology (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-20120172570-A1 | AROMATIC POLYESTER | NITTA CORPORATION | 2012-07-05 | — | — | US | disclosed |
| US-8129493-B2 | Aromatic polyester | MURORAN INSTITUTE OF TECHNOLOGY (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20110224343-A1 | MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME | MURORAN INSTITUTE OF TECHNOLOGY (JP) | 2011-09-15 | — | — | US | disclosed |
| US-20110092662-A1 | AROMATIC POLYESTER | NITTA CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
| US-5214125-A | Polyamide from 3,5-tricyclo[5.2.1.02.6 ]decane dicarboxylic acid | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0332425-B1 | PROCESS FOR REFINING 1,3-DIMETHYL-2-IMIDAZOLIDINONE AND A PROCESS FOR PREPARING AN AROMATIC POLYAMIDE BY USE OF THE REFINED PRODUCT | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-27 | — | — | EP | disclosed |
| EP-0476583-A2 | Novel polyamide and process for the production thereof | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-25 | — | — | EP | disclosed |
| US-5075406-A | Solution polymerization of polyamides in solvent purified by adsorption on magnesia, alumina, silica or mixed oxides | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-12-24 | — | — | US | disclosed |
| US-5011936-A | Using composite salt consisting of at least two of silica, magnesia and alumina | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-04-30 | — | — | US | disclosed |
| US-4923951-A | DIISOCYANTE, ALKALI OR ALKALINE EARTH METAL CATALYST | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1990-05-08 | — | — | US | disclosed |
| US-4910291-A | From aromatic diacid | MITSUBISHI RAYON COMPANY LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0332425-A1 | Process for refining 1,3-dimethyl-2-imidazolidinone and a process for preparing an aromatic polyamide by use of the refined product | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-09-13 | — | — | EP | disclosed |
| EP-0328342-A2 | Process for producing aromatic polyamides | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-08-16 | — | — | EP | disclosed |
| JP-S58194837-A | PREPARATION OF DIPHENYLMETHANE DERIVATIVE | TOA EIYOU KAGAKU KOGYO KK | 1983-11-12 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232107-A1 | NON-PEPTIDE ANTAGONISTS OF GASTRIN RELEASING PEPTIDE | GRPR, GIPR, CCKBR | TSHR 189/4885CA1 565/4885CA2 1018/4885 |
| US-20110224343-A1 | MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME | F12, PHAX, WDR82 | TSHR 3263/4885CA1 550/4885CA2 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.