Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.37 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27947502 | 0.76 | KDM4E (0.46) | KDM4ECYP11B2OPRM1OPRL1 | |
| SCHEMBL7422542 | 0.74 | POLB (0.49) | KDM4ETP53POLBHDAC1HDAC8 | |
| SCHEMBL2713004 | 0.73 | KDM4E (0.49) | KDM4ETP53POLBHDAC1HDAC8 | |
| SCHEMBL16789935 | 0.72 | KDM4E (0.52) | KDM4ETP53POLBELANECHRNA10 | |
| SCHEMBL7421728 | 0.71 | ALDH1A1 (0.57) | TP53POLB | |
| SCHEMBL23299517 | 0.70 | GRM2 (0.43) | KDM4ETP53POLBHDAC1HDAC8 | |
| SCHEMBL7406708 | 0.70 | HTR1A (0.49) | KDM4ETP53POLBHDAC1HDAC8 | |
| SCHEMBL4586702 | 0.70 | ALDH1A1 (0.51) | KDM4ETP53POLB | |
| SCHEMBL20639714 | 0.69 | SLC6A2 (0.47) | KDM4ETP53POLBELANECTSG | |
| SCHEMBL7282701 | 0.69 | KDM4E (0.45) | KDM4ETP53POLBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1054842-C | Platelet aggregation inhibitors | SEARLE & CO (US) | 2000-07-26 | — | — | CN | disclosed |